OR Study

Mali Uganda

Spatial repellents (SR) have the potential of being critical tools in the prevention of mosquito borne diseases in contexts where typical vectors control efforts such as bed nets and indoor residual spraying are inaccessible or underutilized such as among displaced peoples or in emergency relief settings. Malaria endemic sites where ongoing humanitarian relief efforts are underway were selected to estimate the impact of SRs on malaria related outcomes. The study will measure the direct effect of SRs as well as the protective equivalency using varied distribution channels: paid study personnel, community health workers, and a voucher system.

Study Objectives:

  1. To evaluate the protective efficacy of SRs against the first-time malaria infection in pregnant women and children under five in Mali and Uganda;
  2. To investigate the relationship between the reduction in malaria hazard rates and the decrease in mosquito CDC-light trap collection density in Mali and Uganda
  3. To compare the protective efficacy of SRs between product delivery mechanisms (Community Health Workers delivering products to subjects and subjects receiving a voucher to get the product at local health facility and applying at home themselves) versus the reference mechanism (study team personnel delivering product directly to subjects at their homes.

Study Location and Population: As of June 30, 2017, there are nearly 1 million South Sudanese refugees in Uganda. Bidibidi refugee camp is currently the second largest refugee settlement in the world. About 40% of the population in Bidibidi is living in grass thatched roof houses with over 60% living in tarpaulin shelters, with the majority of those being women and children under 18. The population of Mali has suffered from severe and recurring, negative consequences of regular flooding, as well as significant conflict-induced displacement. The study location in Niono Cercle of Segou Region maintains the highest mosquito biting rates in the country that is directly linked to high malaria incidence in the area. Study participants will include children ages 6 to 59 months and pregnant women who report sleeping in selected study clusters.

In-Country Project Lead: Catholic Relief Services

Additionally, social science methodologies and health and market analyses will provide evidence for the acceptability and scalability of implementation. To ensure the SR product is adopted as a complementary vector control tool, findings will be disseminated to the scientific community, end users, and project stakeholders.