AEGIS Consortium members are academic institutions, governmental agencies, and NGOs responsible for the project’s outputs and serve integral roles in project implementation and success. Additional project partners providing guidance and support to the AEGIS program include an industry partner, clinical research organizations, and implementing partner.
Catholic Relief Services (CRS) is one of the world’s largest private voluntary organizations, supporting international relief and development work in more than 100 countries and territories around the world. CRS will conduct a cluster randomized control trial to test the protective efficacy of spatial repellents against malaria and other vector borne diseases, as well as operations research to determine the most effective and efficient mechanisms for distribution of those repellents.
- CRS Partners: Suzanne Van Hulle, John Hembling, Momar Mbodji, Mamadou Diango Traore
The Centers for Disease Control and Prevention (CDC) has established research collaborations with the Kenya Medical Research Institute (KEMRI) in Kenya. This collaboration has evolved into the KEMRI/CDC Field Station in Nyanza Province in western Kenya which will serve as the site for a study of the incidence of malaria in villages with or without spatial repellents. The CDC will provide technical expertise in entomology and epidemiology while KEMRI manages the trial in country conducting baseline surveys, deploying spatial repellents, and monitoring efficacy of spatial repellents for reducing mosquito biting and malaria around the study site.
- CDC Partners: John Gimnig (Entomology PI), Rebecca Levine (Epidemiology PI), Wycliffe Odongo
- KEMRI Partners: Eric Ochomo (Lead PI), Grace Chumbe (Administration), Vincent Moshi (Data Management Lead), Bernard Abong'o (Entomology Lead), Prisca Oria (Social Science Lead), Quentin Awori (Epidemiology Lead)
The Johns Hopkins Center for Communication Programs (JHU) has over 30 years of experience working on designing communication solutions to solve public health problems throughout Asia, Africa, and the Americas, on a variety of health issues including Malaria and Zika. Using social science theories, JHU is able to understand perceptions around prevention measures, diseases, and treatment and how these impact actual behaviors. For the AEGIS project, JHU will be responsible for design, implementation and analysis of the social science components of the project.
- JHU Partners: Steve Harvey (PI), April Monroe (Co-PI), Danielle Piccinini (Program Officer), Kaci McCoy (Operations Manager), Albert Casella, Samantha Wanling Tsang
The National Dengue Control Unit – Sri Lanka (NDCU) will carry out longitudinal field studies in Colombo, Sri Lanka to demonstrate that spatial repellent products reducing the incidence of Aedes-borne human virus infection.
- NDCU Partners: Hasitha Korelege (PI), Anoja Dheerasinghe (Co-PI)
FHI Clinical is a clinical research organization with the responsibility of conducting clinical monitoring at the protocol implementation level, ensuring that subjects are properly consented, data are appropriately gathered, safety events are documented and reported as required, investigational product is stored, distributed and collected per specifications, and that study close-out activities occur on a timely basis.
- FHI Clinical Partners: Silver Wevill, Loice Magaria, Rose Adeny, Zakaria Gansane, Kornchanok (Aimy) Palawooth
SC Johnson, A Family Company (SCJ) is a leader in the development and marketing of Spatial Repellent products. SCJ has a team of experts in the fields of medical entomology, product research and development, social behavior change, and market shaping and access. They have been at the forefront of driving the policy decisions to advance the category of spatial repellents to WHO recommendation for vector control. As such, they have a keen insight into the data requirements, key stakeholders and pathway for transition and scale-up.
- SCJ Partners: David Eland, Tom Putzer, Tom Mascari, Todd Ulrich
The Malaria Research and Training Center (MRTC), out of the University of Bamako, is one of the largest research centers in Africa with excellence in the epidemiology and biology of vectors and parasites of malaria and other vector-borne diseases. MRTC is a core research partner for the implementation of the cRCT in Mali.
- MRTC Partners: Issaka Sagara, Mamadou Coulibaly, Alassane Dicko
Through unique access to a wide network of tertiary-care hospitals around the country, RemediumOne facilitates clinical trials in Sri Lanka with complete management services from submission to close out.
- RemediumOne Partners: Chamini Kanatiwela de Silva (Project Lead)
The Center for Research Computing (CRC) housed at the University of Notre Dame provides the data management infrastructure for the AEGIS program. Activities for the CRC include development of data collection forms, collaboration with in-country data entry personnel, and establishment of data processes like mining and cleaning.
- CRC Partners: Jarek Nabrzyski, Bradley Sandberg, Matthew Noffsinger, Noel Recla, David Pettifor, Samuel Njoroge, Jessica Yang, Kinsey Poland